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1H mrs of human brain abscesses in vivo and in vitro

✍ Scribed by Chantal Rémy; Sylvie Grand; Ernest Sam Laï; ValéRie Belle; Dominique Hoffmann; FrançOis Berger; FrançOis Estève; Anne Ziegler; Jean-FrsançOis Le Bas; Alim L. Benabid; Michel Décorps; Christoph M. Segebarth

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
849 KB
Volume
34
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Five patients, each with a brain abscess, were examined by means of ^1^H MR spectroscopic imaging in vivo. The aspirated pus was analyzed in vitro by means of 1D and 2D COSY ^1^H MRS. In addition to resonance lines from compounds (lactate, alanine and lipids) often found in the spectra from intracranial tumors, resonance lines were detected from a number of markers of infectious involvement (acetate, succinate, and various amino acids). These results suggest that ^1^H MRS in vivo might contribute in establishing noninvasively a differential diagnosis between brain abscess and tumor.

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