1H-Imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: Separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka

✍ Scribed by Wullie Arbuckle; Mark Baugh; Simone Belshaw; D. Jonathan Bennett; John Bruin; Jiaqiang Cai; Kenneth S. Cameron; Chris Claxton; Maureen Dempster; Kathryn Everett; Xavier Fradera; William Hamilton; Philip S. Jones; Emma Kinghorn; Clive Long; Iain Martin; John Robinson; Paul Westwood

• Publisher: Elsevier Science
• Year: 2011
• Tongue: English
• Weight: 363 KB
• Volume: 21
• Category: Article
• ISSN: 0960-894X
• DOI: 10.1016/j.bmcl.2010.12.065