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1H editing of 2-deuterated exogenous and natural endogenous D-glucose in biological samples

✍ Scribed by Monique Biesemans; François Kayser; Marc Van Cauteren; Nancy J. Rehrer; Peter Neirinck; Kenny De Meirleir; Willy J. Malaise; Rudolph Willem

Book ID: 102533250
Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 437 KB
Volume: 30
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910300118

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✦ Synopsis

Abstract

A spin‐echo based ^1^H homonuclear pulse sequence, enabling the selective editing of homonuclear first‐order J‐multiplet types, is presented and analyzed. Its effectiveness in quantification applications is assessed. Its potential usefulness in the quantitative distinction between 2‐deuterated and natural D‐,glucose in biological samples is briefly discussed, with emphasis on studies of hexose metabolism conducted in vitro.

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