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1H and 13C NMR spectral characterization of some antimalarial in vitro 2,4-diamino-10-methylpyrimido[4,5-b]-5-quinolone derivatives

✍ Scribed by Jaime E. Charris; José N. Domínguez; Neira Gamboa; Jorge Angel; Nolberto Piña; Mayamarú Guerra; Elba Michelena; Simón E. López

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
89 KB
Volume
40
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

We report the ^1^H NMR and ^13^C NMR chemical shifts and J(H,H), J(H,F) and J(C,F) coupling constants of 13 2,4‐diamino‐10‐methylpyrimido[4,5‐b]‐5‐quinolone derivatives, some of them with moderate activity against Plasmodium falciparum in vitro. They were characterized and assigned on the basis of ^1^H, ^13^C and ^13^C–^1^H (short‐ and long‐range) correlated spectra. Copyright © 2002 John Wiley & Sons, Ltd.

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