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1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one induces cell cycle arrest and apoptosis in HeLa cells by preventing microtubule polymerization

✍ Scribed by So Young Kim; Jeong Mi An; Han Gil Lee; Sik Kim Du; Chae Uk Cheong; Jeong Taeg Seo


Book ID
116301663
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
645 KB
Volume
408
Category
Article
ISSN
0006-291X

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1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-
✍ Han Gil Lee; So Young Kim; Du Sik Kim; Su Ryeon Seo; Syng-Ill Lee; Dong Min Shin πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 335 KB

## Abstract The effect of the potent soluble guanylyl cyclase (sGC) inhibitor 1__H__‐[1,2,4]oxadiazolo[4,3‐__a__]quinoxalin‐1‐one (ODQ) on neurite outgrowth and retraction was investigated in PC12 cells and SH‐SY5Y human neuroblastoma cells. ODQ inhibited neurite outgrowth and triggered neurite ret