19F NMR studies of solvent exposure and peptide binding to an SH3 domain
β Scribed by Ferenc Evanics; Julianne L. Kitevski; Irina Bezsonova; Julie Forman-Kay; R. Scott Prosser
- Book ID
- 116271766
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 842 KB
- Volume
- 1770
- Category
- Article
- ISSN
- 0304-4165
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## Abstract We have determined the thermodynamic stability and peptide binding affinity of the carboxyβterminal Src homology 3 (SH3) domain from the __Caenorhabditis elegans__ signalβtransduction protein Semβ5. Despite its small size (62 residues) and lack of disulfide bonds, this domain is highly