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199Effects of a new oncolytic adenovirus (XVIR) in human prostate cancer cell lines and in xenograph mouse model

✍ Scribed by U. Treiber; K. Mantwill; N. Köhler Vargas; A. Bernshausen; R. Paul; H. Van Randenborgh; H. Kübler; N. Zantl; R. Hartung; B. Gänsbacher; P.S. Holm

Book ID: 118646333
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 198 KB
Volume: 4
Category: Article
ISSN: 1569-9056
DOI: 10.1016/s1569-9056(05)80208-8

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## Abstract ## Background Although cancer therapy using replication‐selective oncolytic adenoviruses has been available for many years, its anti‐tumor efficacy is suboptimal as a result of low and nonspecific infectivity that depends on coxsackie adenovirus receptor expression of the target cancer