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199 Sequential topoisomerase targeting triplet chemotherapy with irinotecan/cisplatin followed by doxorubicin in patients with malignant pleural mesothelioma: A pilot phase II study

✍ Scribed by Nakano, T.; Fukuoka, K.; Kuribayashi, K.; Uesaka, A.; Miyata, S.; Miyake, M.


Book ID
118573882
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
46 KB
Volume
54
Category
Article
ISSN
0169-5002

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Cisplatin in combination with irinotecan
✍ Takashi Nakano; A. Philippe Chahinian; Miho Shinjo; Naoki Togawa; Atsushi Tonomu πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 161 KB πŸ‘ 2 views

The purpose of this study was to assess the efficacy and toxicity of a combination of cisplatin and irinotecan (CPT-11) in the treatment of patients with malignant pleural mesothelioma and to characterize the pharmacokinetic profiles of CPT-11 and its active metabolite, 7-ethyl-10-hydroxycamptotheci