195 Heparinbinding EGF-like growth factor is hyperexpressed and coexpressed with CD9 in psoriatic epidermis

Possible role of coexpression of CD9 wit

Possible role of coexpression of CD9 with membrane-anchored heparin-binding EGF-like growth factor and amphiregulin in cultured human keratinocyte growth

✍ Shigeki Inui; Shigeki Higashiyama; Koji Hashimoto; Mari Higashiyama; Kunihiko Yo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

CD9 is a protein with 4 transmembrane domains, and functions as a cell surface antigen. We have previously reported that CD9 functions as an up-regulator of membrane-anchored heparin-binding EGF-like growth factor (proHB-EGF) activity, which is a potent mitogen as well as a soluble HB-EGF. Anti-CD9