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192 New targeted therapies strategies in hepatocellular carcinoma - In vitro studies

✍ Scribed by A.M. Araújo; S. Sousa Neves; A.L. Ferreira; J.D. Branco; A.B. Sarmento Ribeiro; J.M. Nascimento Costa

Book ID
119602873
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
61 KB
Volume
8
Category
Article
ISSN
1359-6349

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Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with several genomic alterations. There is evidence of aberrant activation of several signaling cascades such as epidermal growth factor receptor (EGFR), Ras/extracellular signal-regulated kinase, phosphoinositol 3-kinase/mammalian