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1,9-Stereocontrol from 1,7-induction using an allylstannane followed by an Ireland-Claisen rearrangement

✍ Scribed by Ella-Maria Moffatt; Eric J Thomas


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
783 KB
Volume
55
Category
Article
ISSN
0040-4020

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1,8-Stereocontrol by 1,5-induction using
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The relative configurations of 1,8-stereogenic centres can be controlled by coupling the tin(IV) chloride promoted reactions of aldehydes with 4-alkoxypent-2-enylstannanes, which proceed with excellent 1,5-induction, with an Ireland-Claisen rearrangement: this approach has been used to complete a di

1,8-Stereocontrol by 1,5-induction using
✍ E.Kate Dorling; Andrew P. Thomas; Eric J. Thomas πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 119 KB

The relative configurations of 1,8-stereogenic centres can be controlled by coupling the tin(IV) chloride promoted reactions of aldehydes with 4-alkoxypent-2-enylstannanes, which proceed with excellent 1,5-induction, with a 2,3-Wittig rearrangement: this approach has been used to complete a diastere