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18O-labeled nucleosides 3. Preparation and mass spectrometric evaluation of 18O2-labeled ara-C and ara-U

✍ Scribed by Ernst M. Schubert; Karl H. Schram


Publisher
John Wiley and Sons
Year
1982
Tongue
French
Weight
247 KB
Volume
19
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

A facile method for the preparation of ^18^O labeled ara‐C and ara‐U is described. The method provides a means of incorporating ^18^O specifically at the 2‐position of the nucleobase. The site and level of label was established using mass spectrometry.