Rapid production and trapping of [18F]fl
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S.John Gatley
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Article
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1989
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Elsevier Science
β 290 KB
A flow-through system is described for rapid purification of [18F]fluoride for nucleophilic substitution reactions. It depends on generation of [18F]fluorotrimethylsilane from aqueous 18F solutions and subsequent collection of the gas and its hydrolysis by base in near anhydrous acetonitrile. Potass