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[18F]3′-deoxy-3′-fluorothymidine PET for the diagnosis and grading of brain tumors

✍ Scribed by Seung Jin Choi; Jae Seung Kim; Jeong Hoon Kim; Seung Jun Oh; Jeong Gyo Lee; Chang Jin Kim; Young Shin Ra; Jeong Seok Yeo; Jin Sook Ryu; Dae Hyuk Moon

Publisher
Springer
Year
2005
Tongue
English
Weight
771 KB
Volume
32
Category
Article
ISSN
0340-6997

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✍ M. M. Alauddin; J. Balatoni; J. Gelovani 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 201 KB 👁 1 views

The synthesis of a pyrimidine analog, 3 0 -deoxy-3 0 -[ 18 F]-fluoro-1-b-d-xylofuranosyluracil ([ 18 F]-FMXU) is reported. 5-Methyluridine 1 was converted to its dimethoxytrityl derivatives 2 and 3 as a mixture. After separation the 2 0 , 5 0 -di-methoxytrityluridine 2 was converted to its 3 0 -trif