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181 The binding of inhibitors to carbonic anhydrase in vivo: drugs as markers for enzyme

โœ Scribed by T.H. Maren


Book ID
115767765
Publisher
Elsevier Science
Year
1961
Tongue
English
Weight
114 KB
Volume
8
Category
Article
ISSN
0006-2952

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Red cell carbonic anhydrase is identified as an ideal target in an enzyme-inhibitor approach to radiolabel localisation. Current problems in blood pool labelling could be overcome by using selective sulphonamide inhibitors as carriers. p-Iodobenzenesulphonamide (pIBS) was selected as the choice reag