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17O-Decoupled 1H Spectroscopy and Imaging with a Surface Coil: STEAM Decoupling

✍ Scribed by Sridhar R Charagundla; Umamaheswar Duvvuri; Elizabeth A Noyszewski; Rahul Dandora; Alan H Stolpen; J.S Leigh; Ravinder Reddy

Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 140 KB
Volume: 143
Category: Article
ISSN: 1090-7807
DOI: 10.1006/jmre.1999.1948

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✦ Synopsis

(17)O-decoupled (1)H spin-echo imaging has been reported as a means of indirect (17)O detection, with potential application to measurement of blood flow and metabolism. In its current form, (17)O decoupling requires large RF amplitudes and a 180 degrees refocusing pulse, complicating its application in volume and surface coils, respectively. To overcome this problem, we have developed an (17)O-decoupled proton stimulated echo sequence ("STEAM decoupling") to allow (17)O detection with a surface coil. A high B(1) amplitude is easily generated, allowing complete decoupling of (17)O and (1)H. Slice-selective, (17)O-decoupled (1)H imaging is readily performed and the sequence is easily adapted for localized spectroscopy. Intrinsic correction for variations in B(1) and further compensation for B(1) inhomogeneity are discussed.

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