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177 Esophageal Squamous Cell Cancer in a Transgenic Mouse Model of KLF4

✍ Scribed by Marie-Pier Tetreault; Mei-Lun Wang; Bree G. Goldstein; Yizeng Yang; Qian-Chun Yu; Andres J. Klein-Szanto; Anil K. Rustgi; Jonathan P. Katz

Book ID
119428022
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
108 KB
Volume
134
Category
Article
ISSN
0016-5085

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## Abstract __Background.__ A murine model of oral cavity carcinogenesis is needed to study the molecular aspects of malignant transformation. 4‐Nitroquinoline‐1‐oxide (4NQO), a water‐soluble carcinogen, produces squamous cell carcinoma in rodents. Protocols were designed to investigate the tempora