166. Newly discovered protein–protein interactions of schizophrenia associated genes and their biomedical significance

Association studies and gene expression

Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder

✍ Ayyappan Anitha; Kazuhiko Nakamura; Kazuo Yamada; Yoshimi Iwayama; Tomoko Toyota 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 136 KB 👁 2 views

## Abstract Disrupted‐in‐Schizophrenia 1 (DISC1) and its molecular cascade have been implicated in the pathophysiology of major psychoses. Previously, we identified pericentrin 2 (PCNT2) and DISC1‐binding zinc finger protein (DBZ) as binding partners of DISC1; further, we observed elevated expressi