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164 Five-year Survival and Prognostic Factors in a Cohort of Breast Cancer Patients Treated in Brazilian National Cancer Institute, Rio De Janeiro, Brazil

✍ Scribed by M. Bello; E.C. Millen; P.A.O. Carmo; R.C. Motta; L.C.S. Thuler; A. Bergmann


Book ID
117662075
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
76 KB
Volume
48
Category
Article
ISSN
0959-8049

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TP53 mutations in breast cancer tumors o
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Somatic mutations in the TP53 gene are the most frequently observed genetic alterations in human malignancies, including breast cancer, which is one of the leading causes of death among women in Brazil. In our study, we determined the frequency and the pattern of TP53 mutations in malignant breast t