## Abstract ## BACKGROUND The presence of isolated tumor cells (ITC) in the bone marrow at the time of primary diagnosis indicates an increased risk for subsequent development of distant metastases in various solid tumors. This study evaluates the prevalence and prognostic significance of ITC in p
160 Patterns of relapse influenced by hematogenous tumor cell dissemination in patients with cervical carcinoma of the uterus
โ Scribed by H. Sommer; W. Janni; B. Rack; B. Strobl; D. Rjosk; C. Schindlbeck; W. Thieleke; F. Hepp; S. Braun; K. Friese
- Book ID
- 118620335
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 327 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1359-6349
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## Abstract Despite an extensive surgical approach only 50% of the patients with medullary thyroid carcinoma (MTC) are biochemically cured. The failure to cure a larger number of patients is a result of the early dissemination of MTC. The present study evaluates two RTโPCR based assays for the dete
## Abstract Detection of disseminated tumor cells (DTCs) in bone marrow is an independent prognostic factor in primary breast cancer. Here, we conducted a proofโofโprinciple study to evaluate whether this tumor cell spread occurs already in patients with ductal carcinoma in situ (DCIS). After preop