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16 TPS in breast cancer

✍ Scribed by J.F.R. Robertson; J. Beaver; D. Pearson; A. Gilmore; P. Willsher; K. O'Neill; P.G. McKenna


Book ID
113404469
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
162 KB
Volume
4
Category
Article
ISSN
0960-9776

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Mutation in p53 (TP53) remains one of the most commonly described genetic events in human neoplasia. The occurrence of mutations is somewhat less common in sporadic breast carcinomas than in other cancers, with an overall frequency of about 20%. There is, however, evidence that p53 is mutated at a s