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1,6-Additionen an 3-Methyl-5-methyliden-2-(5H)-furanon-Derivate

✍ Scribed by Heinz Wyss; Laszlo Révész; Rolf Scheffold

Book ID
102250637
Publisher
John Wiley and Sons
Year
1981
Tongue
German
Weight
462 KB
Volume
64
Category
Article
ISSN
0018-019X

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✦ Synopsis

1,6‐Additions to 3‐Methyl‐5‐methylidene‐2(5__H__)‐furanone Derivatives

The anions of thiophenol, methyl malonate and malononitrile react with 3‐methyl‐5,6‐dihydro‐2 (4__H__)‐benzofuranone (1c) by the formation of the corresponding 1,6‐addition products cis‐5c (63%), trans‐6 (42%) and trans‐7 (76%), respectively. Likewise, the reaction of 3‐methyl‐5‐methylidene‐2 (5__H__)‐furanone (1b) with thiophenol yields the 1,6‐addition product 5b (66%), and with the sodium salt of methyl aceto‐acetate the 1,6‐addition product 8 (11%) and the dispiro‐dilactone 9 (39%).

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Mucochloric Acid: A Useful Synthon for t
Mucochloric Acid: A Useful Synthon for the Selective Synthesis of 4-Aryl-3-chloro-2(5H)-furanones, (Z)-4-Aryl-5-[1-(aryl)methylidene]-3-chloro-2(5H)-furanones and 3,4-Diaryl-2(5H)-furanones
✍ Fabio Bellina; Chiara Anselmi; Francesca Martina; Renzo Rossi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB 👁 1 views

## Abstract 3,4‐Dichloro‐2(5__H__)‐furanone, which has been prepared efficiently from mucochloric acid, has been transformed selectively into 4‐aryl‐3‐chloro‐2(5__H__)‐furanones either by Suzuki‐ or Stille‐type reactions. These monochloro derivatives have been used as precursors either to (__Z__)‐4