15α-Hydroxylation of 13-ethyl-gon-4-ene-3,17-dione using a hyphal fungus immobilized in calcium alginate gel beads

✍ Scribed by D. Schlosser; Prof. Dr. H.-P. Schmauder

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 339 KB
• Volume: 31
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/jobm.3620310518

✦ Synopsis

Calcium alginate-entrapped mycelium of Penicillium raistrickii i 477 was used for the 15a-hydroxylation of 13-ethyl-gon-4-ene-3,17-dione. The system was tested in 10 batches during 40 days of operation, the catalytic activity could be completely regenerated by incubation in a nutrient medium between several batches.

* 7 H,O, 0.002% FeSO, * 7 H,O and 0.05% KCl (w/v) (PETZOLDT and WIECHERT 1976) were inoculated 0 ' & *o&OH "