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15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells

✍ Scribed by Hyun-Joung Lim; Kuy-Sook Lee; Seahyoung Lee; Jin-Hee Park; Hye-Eun Choi; Sang Hee Go; Hyun-Jeong Kwak; Hyun-Young Park

Book ID: 113924147
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 882 KB
Volume: 223
Category: Article
ISSN: 0041-008X
DOI: 10.1016/j.taap.2007.04.019

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## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate smooth muscle cell proliferation, migration, and vascular maturation. S1P increases the expression of several proteins including COX‐2 in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mecha