156 Regulation of Cyclin-Dependent Kinase 2 (CDK2) Gene Transcription Through MicroRNA-29b in Intestinal Epithelial Cells by Polyamines

Transcriptional regulation of IL-8 by ir

Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-κB but involves ERK1/2- and p38 kinase-dependent activation of AP-1

✍ Eun-Young Choi; Zee-Yong Park; Eun-Ju Choi; Hyun-Mee Oh; SungGa Lee; Suck-Chei C 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 402 KB 👁 2 views

## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in