1548 Differential neurotoxicity of MPTP to substance P vs enkephalin neurons in the rat striatum
โ Scribed by Ikai, Yoshiaki; Takada, Masahiko; Mizuno, Noboru
- Book ID
- 122954776
- Publisher
- Elsevier Science
- Year
- 1993
- Weight
- 92 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0921-8696
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It is well known that striatonigral neurons produce substance P (SP); however, no SP receptor (SPR) has so far been found in the substantia nigra. On the other hand, a previous study in the rat striatum indicated that SPR was expressed only in cholinergic or somatostatinergic intrinsic neurons (Kane
The serotonergic innervation of the hypoglossal nucleus originates from the caudal raphe nuclei. Non-serotonergic neurons in the caudal raphe nuclei also project to the hypoglossal nucleus. We employed a triple-fluorescence technique to determine whether the substance P- or the enkephalin-containing