154 DIFFERENTIAL EFFECT OF CALCINEURIN INHIBITORS, TACROLIMUS AND CYCLOSPORINE A, ON INTERFERON INDUCED ANTI-VIRAL PROTEIN IN HUMAN HEPATOCYTE CELL

Differential effects of calcineurin inhi

Differential effects of calcineurin inhibitors, tacrolimus and cyclosporin a, on interferon-induced antiviral protein in human hepatocyte cells

✍ Kumi Hirano; Tatsuki Ichikawa; Kazuhiko Nakao; Azusa Matsumoto; Hisamitsu Miyaak 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB 👁 1 views

The premise of our study is that selective inhibition of interferon (IFN) by calcineurin inhibitors contribute to the increased severity of hepatitis C virus (HCV) posttransplantation. Therefore, we examined the influence of calcineurin inhibitors in the human hepatocyte cell line on IFN-alpha-induc