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153 Influence of sex difference on the pharmacological action and catabolism of some drugs

โœ Scribed by R. Kato; E. Ghiesara; G. Fontino

Book ID
115767736
Publisher
Elsevier Science
Year
1961
Tongue
English
Weight
116 KB
Volume
8
Category
Article
ISSN
0006-2952

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The effect of variable protein binding (taken as independent parameter) on pharmacological activity of drugs is considered in terms of the exposure or the steady state concentration of unbound drug at targeted tissue. Based on the application of the parallel tube or dispersion models it is shown tha