1–51 The prevalence of germline BRCA1 and BRCA2 mutations in young women with breast cancer undergoing breast-conservation therapy
✍ Scribed by Moran, M.S.; Haffty, B.G.
- Book ID
- 122425150
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 132 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1043-321X
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## Abstract Our aim was to estimate the prevalence of mutations in the __BRCA1__ and __BRCA2__ genes among unselected incident cases of breast cancer in young women. We identified 158 incident breast cancer cases diagnosed before age 46 years in predefined geographic areas in Girona and Tarragona,
In order to evaluate the role of BRCA1 and BRCA2 germline mutations in Korean patients with sporadic breast cancer, 97 patients with sporadic breast cancer were analyzed for mutations in the BRCA1 and BRCA2 coding regions, by using a combination of fluorescent-conformation sensitive gel electrophore