151 Immunogenicity of chimeric (Fc portion is human) anti-idiotypic monoclonal antibody MK2-23, an internal image of human high molecular weight-melanoma associated antigen

Improved tumor targeting of rhenium-186-

Improved tumor targeting of rhenium-186-labeled anti-human high-m.w. melanoma-associated antigen monoclonal antibody 763.74 following purification with anti-idiotypic monoclonal antibody MK2–23

✍ Carl V. Hamby; Marco Chinol; Christopher J. Palestro; Ciro Manzo; Soldano Ferron 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 101 KB

Because of its high-energy beta emissions and imageable gamma emissions, 186 Re represents an attractive isotope to radiolabel monoclonal antibodies (MAbs) recognizing human tumor-associated antigens (TAAs) for radioimmunoscintigraphy (RIS) and radioimmunotherapy (RIT) of patients with malignant dis