𝔖 Bobbio Scriptorium
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1502 INTERACTION OF DARIFENACIN WITH DRUG EFFLUX TRANSPORTERS: IMPLICATIONS IN THE BLOOD-BRAIN BARRIER PERMEABILITY OF THE DRUG

✍ Scribed by Miller, Donald; Chen, Fang; Hinton, Martha

Book ID
122472340
Publisher
Lippincott Williams and Wilkins
Year
2010
Tongue
English
Weight
46 KB
Volume
183
Category
Article
ISSN
0022-5347

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Evaluation of drug efflux transporter li
Evaluation of drug efflux transporter liabilities of darifenacin in cell culture models of the blood–brain and blood–ocular barriers
✍ Donald W. Miller; Martha Hinton; Fang Chen 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB

## Abstract ## Aims The objective of the present study was to evaluate drug efflux transporter interactions of darifenacin and examine the impact of such transporter interactions on darifenacin permeability in an __in vitro__ model of the blood–brain barrier (BBB) and blood–ocular barrier (BOB).