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15-Oxygenated sterols by m-chloroperbenzoic acid oxidation of 3.beta.-acetoxy-5.alpha.-cholesta-8,14-diene

✍ Scribed by Anastasia, Mario; Allevi, Pietro; Fiecchi, Alberto; Scala, Antonio


Book ID
127016166
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
370 KB
Volume
46
Category
Article
ISSN
0022-3263

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Chemical syntheses of 5α-cholesta-6,8(14
✍ Edward J. Parish; George J. Schroepfer Jr. 📂 Article 📅 1979 🏛 Elsevier Science 🌐 English ⚖ 785 KB

Hydroboration of 5a-cholesta-8,14-dien-3fl-ol ( ) gav e 5a-cholest-8-en-3CLl5a-diol (IV) in 89% yield. 5a-Cholest-7-en-3/3,15a-diol (V) was prepared in 91% yield by hydroboration of 5ct-cholesta-7,14-dien-3/3-ol (H). Hydroboration of 27:63 mixture of I and H gave IV and V in 18% and 70% yields, resp