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1,5-Disubstituted imidazoles inhibit juvenile hormone biosynthesis by the corpora allata of the mosquito Aedes aegypti

✍ Scribed by Yiping Li; Eiichi Kuwano; Fernando G. Noriega

Book ID
114052814
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
154 KB
Volume
49
Category
Article
ISSN
0022-1910

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I-Citronellyl-5-phenyl imidazole (1,5-CPI), l-citronellyl-4-phenyl imidazole (I,& CPI) and I-citronellyl-2-phenyl imidazole (1,2-CPI) were tested as inhibitors of JH-Ill biosynthesis in vitro. 1,5-CPI was found to be most active followed by 1,2-CPI. The least active isomer was 1,4-CPI. Inhibition of