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1,5-Diazabicyclo[4.3.0.] nonane, the oxidation product of spermine

✍ Scribed by S.J. Croker; R.S.T. Loeffler; T.A. Smith; B. Sessions


Book ID
104217159
Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
105 KB
Volume
24
Category
Article
ISSN
0040-4039

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✦ Synopsis


The structure of the product of the chemical or enzymatic oxidation of spermine was shown to be 1,5-diaaabicyclo[4.3.0.]nonane (III). The importance of naturally-occurring polyamines in the regulation of many biological processes' has recently stimulated research into their metabolism. It has long been known


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Design and Synthesis of 1,4-Diazabicyclo[4.3.0]nonane Peptidomimetic Endothelin Antagonists. -Four peptidomimetics such as (XI) are synthesized in order to examine the effect of the carboxyl group stereochemistry on the biological activity. The structures of the peptidomimetics are based on the pep