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148 Oxidative stress and inflammation in cystic fibrosis (CF)

โœ Scribed by A. De Alessandri; M.P. Ierardi; C. Zucchi; R. Casciaro; L. Minicucci

Book ID
117799660
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
61 KB
Volume
11
Category
Article
ISSN
1569-1993

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Nitric oxide (NO) is produced from three isoforms of nitric oxide synthase (NOS), neuronal (nNOS), endothelial (eNOS) and inducible (iNOS). Cystic ยฎbrosis (CF) patients have an increased bacterial load in the airways which stimulates iNOS and therefore NO production. Upregulation of iNOS in normal e