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142 Phase II study of imatinib mesylate in salivary gland adenoid cystic carcinoma

✍ Scribed by E. Winquist; E. Lamont; S. Hotte; M. MacKenzie; S. Brown; A. Murgo; L. Siu

Book ID
118620317
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
333 KB
Volume
1
Category
Article
ISSN
1359-6349

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## Abstract ## Background. Adenoid cystic carcinoma (ACC) is a malignant neoplasia of the salivary glands that is treated primarily by surgery. Local control and survival are usually compromised despite surgery. Expression of KIT tyrosine kinase is involved in the pathogenesis of ACC. Imatinib mes