A New Series of M3 Muscarinic Antagonist
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O. Diouf; S. Gadeau; F. Chelle; M. Gelbcke; P. Talaga; B. Christophe; M. Gillard
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Article
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2003
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John Wiley and Sons
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A New Series of M3 Muscarinic Antagonists Based on the 4-Amino-piperidine Scaffold. -Twenty-five new N,N-disubstituted 4-aminopiperidines are synthesized by chemical modulation of aminopiperidine bearing a phenyl and a benzoyl group at the amino group. The main pharmacophoric pattern which allows a