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1,4-diazabicyclo[2.2.2]octane-catalyzed self- and cross-condensation of α-acetylenic ketones

✍ Scribed by P.Veeraraghavan Ramachandran; Michael T. Rudd; M.Venkat Ram Reddy

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
223 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

3-Butyn-2-one condenses with itself in the presence of 0.1 molar equiv of Dabco providing 80% yield of E-3-(1-buten-3-yn-2-oxy)-buten-2-one.

Substitution at the acetylene terminus prevents the condensation. However, such ketones can be condensed with terminal acetylenic ketones to provide the cross-coupled products in high yields.

📜 SIMILAR VOLUMES

DABCO-Directed Self-Assembly of Bisporph
DABCO-Directed Self-Assembly of Bisporphyrins (DABCO=1,4-Diazabicyclo[2.2.2]octane)
✍ Pablo Ballester; Antoni Costa; Ana M. Castilla; Pere M. Deyà; Antonio Frontera; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB 👁 1 views

## Abstract Three isomeric zinc bisporphyrins have been prepared by covalently linking together two aminoporphyrins with an isophthalic acid derivative. The porphyrins differ in the substitution pattern on the __meso__ phenyl groups, that is, __ortho__, __meta__, or __para__. Titrations carried out