## Abstract A conformation of a diketopiperazine, cyclo(LโleucylโLโtryptophyl), was determined by nmr and xโray analysis. The receptor for this bitter diketopiperazine neither recognizes chirality nor requires a strict conformation of the substrate. A good correlation was found between the bitterne
โฆ LIBER โฆ
1,4-Benzodiazepines. Chemistry and Some Aspects of the Structure-Activity Relationship
โ Scribed by Dr. Leo H. Sternbach
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 801 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0044-8249
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## Abstract Naphthoquinone derivatives are under investigation as potential therapeutic agents. Some such compounds are known, however, to be toxic to both animals and humans. Many naphthoquinone derivatives are haemolytic agents, while others cause necrosis of tubular epithelial cells. In the pres