Triterpenes of the betulinic acid type are getting more and more importance because of their interesting pharmacological activities. Especially they display anti-inflammatory [1], antitumor [2], leishmanicidal [3], and antimalarial [4] activities. Most interesting is the fact that betulinic acid, di
13C NMR studies of the triterpene 3α-hydroxylup-20(29)-en-23,28-dioic acid and some derivatives
✍ Scribed by A. Preiss; M. Lischewski; G. Adam; M. Budéšínský
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 435 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0749-1581
No coin nor oath required. For personal study only.
✦ Synopsis
The uC NMR assignment of the triterpene 3a-hydroxylup-20(29)-en-W,28-dioic acid and some of its derivatives has been carried out. In addition to conventional methods, 2D 'H-13C chemical shift correlation, nuclear Overhauser enhancement difference and decoupling Merence techniques were used for the assignment.
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## Abstract 3α‐Acetyl‐20(29)‐lupene‐24‐oic acid (**1**) was isolated from the gum resin of __Boswellia serrata.__ Its presence evidently suggests, that the oxidosqualene triterpene pathway of __Boswellia serrata__ closely resembles the biosynthetic route already found in other plants. Complete ^1^H