13C Isotopomer Analysis of Glutamate by
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Shawn C. Burgess; Rui A. Carvalho; Matthew E. Merritt; John G. Jones; Craig R. M
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Article
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2001
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Elsevier Science
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English
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13C NMR isotopomer analysis is a powerful method for measuring metabolic fluxes through pathways intersecting in the tricarboxylic acid cycle. However, the inherent insensitivity of 13C NMR spectroscopy makes application of isotopomer analysis to small tissue samples (mouse tissue, human biopsies, o