The 3D localized 13C spectroscopy methods LINEPT and LODEPT, which are modifications of INEPT and DEPT, are proposed. As long as a 13C inversion pulse (180-degree pulse) is applied at 1/(4J) before the proton echo time in LINEPT and a 13C excitation pulse (90-degree pulse) is applied at 1/(2J) befor
13C DEPT spectroscopy in vivo of [3-13C]Alanine in rat liver using a 13C surface coil
✍ Scribed by Andreas Dölle
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 288 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-2364
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Alanine is the major amino acid utilized by the liver for gluconeogenesis under normal conditions. The metabolism of alanine in rat liver was investigated by means of 1 H and 13 C NMR spectroscopic studies in vivo and in vitro after infusion of L-and D-alanine labelled with 13 C at the carboxyl and
A single-voxel Carr-Purcell-Meibloom-Gill sequence was developed to measure localized T(2) relaxation times of (13)C-labeled metabolites in vivo for the first time. Following hyperpolarized [1-(13)C]pyruvate injections, pyruvate and its metabolic products, alanine and lactate, were observed in the l