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1,3,4-Thiadiazole Derivatives. Synthesis, Structure Elucidation, and Structure−Antituberculosis Activity Relationship Investigation

✍ Scribed by Oruç, Elçin E.; Rollas, Sevim; Kandemirli, Fatma; Shvets, Nathaly; Dimoglo, Anatholy S.

Book ID: 115469203
Publisher: American Chemical Society
Year: 2004
Tongue: English
Weight: 196 KB
Volume: 47
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm0495632

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## Abstract The aminothiadiazole (II) on treatment with aromatic aldehydes yielded Schiff bases, which cyclized to thiazolidinone derivatives by reaction with thioglycolic acid. Reaction of II with phenyl isocyanate and phenyl isothiocyanate afforded the carbamide and carbothiamide derivatives, res