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130 The effects of glucose depletion on the neurons of rat dorsolateral septum nucleus

โœ Scribed by Tsurusaki, Masashi; Shoji, Shingo; Akasu, Takashi


Book ID
123060103
Publisher
Elsevier Science
Year
1993
Weight
71 KB
Volume
18
Category
Article
ISSN
0921-8696

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The role of glucose in synaptic transmission was examined in the rat dorsolateral septal nucleus (DLSN) with single-microelectrode voltage-clamp and slicepatch techniques. Removal of glucose from the oxygenated Krebs solution caused a n outward current associated with an increased membrane conductan

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Intracellular recordings were made from neurons in the dorsolateral septal nucleus (DLSN) of rat brain slices. Lowering the concentration of extracellular glucose resulted in a concentration-dependent membrane hyperpolarization associated with a cessation of spontaneous firing. The amplitude of the