𝔖 Bobbio Scriptorium
✦   LIBER   ✦

13-P108 Understanding the differences between LRP5 and LRP6

✍ Scribed by Bryan MacDonald; Xi He

Book ID
119328115
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
38 KB
Volume
126
Category
Article
ISSN
0925-4773

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A cell-based Dkk1 binding assay reveals
A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V)
✍ Richard J. Murrills; Jeanne J. Matteo; Bheem M. Bhat; Valerie E. Coleburn; Krist πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 276 KB πŸ‘ 2 views

## Abstract Dkk1 is a secreted antagonist of the LRP5‐mediated Wnt signaling pathway that plays a pivotal role in bone biology. Because there are no well‐documented LRP5‐based assays of Dkk1 binding, we developed a cell‐based assay of Dkk1/LRP5 binding using radioactive ^125^I‐Dkk1. In contrast to