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13-P045 Functional analysis of CHEP12, a novel gene involved in the differentiation of heart precursor cells

✍ Scribed by Margaret Bento; Elizabeth Correia; João Furtado; João Facucho-Oliveira; José A. Belo


Book ID
119328053
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
41 KB
Volume
126
Category
Article
ISSN
0925-4773

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ETV6 (TEL) is rearranged in various types of hematologic malignancies. The B-cell precursor acute lymphoblastic leukemia (ALL) cell line SUP-B2 has a t(6;12)(q23;p13) involving ETV6 at 12p13 and a submicroscopic deletion of the other ETV6 allele. The reciprocal translocation results in the fusion of