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1,3 Dipolar cycloadditions of azomethine ylides with aromatic aldehydes. syntheses of 1-oxapyrrolizidines and 1,3-oxazolidines.

✍ Scribed by F. Orsini; F. Pelizzoni; M. Forte; R. Destro; P. Gariboldi

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
965 KB
Volume
44
Category
Article
ISSN
0040-4020

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✦ Synopsis

Substituted 1-oxapyrrolizidines have been synthetized by cycloaddition of azomethi?e ylides, generated by aldehydes induced decarboxylation of proline, with dipolarophylei.' The carbonyl stbreochernistry of the cycloadducts indicate that they arise from the stereospecific formation of one is6mer of the azomethine ylide.

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