1,3-DIPOLAR CYCLOADDITION REACTIONS OF 3′,5′- BIS - O -SILYL THYMIDINES. SYNTHESIS OF NOVEL AZABICYCLIC COMPOUNDS
✍ Scribed by Negrón, G.; Calderón, G.; Vázquez, F.; Lomas, L.; Cárdenas, J.; Márquez, C.; Gaviño, R.
- Book ID
- 126599566
- Publisher
- Taylor and Francis Group
- Year
- 2002
- Tongue
- English
- Weight
- 133 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0039-7911
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A facile synthesis of novel spiroindane-1,3-diones has been achieved via 1,3-dipolar cycloaddition of an azomethine ylide, generated in situ from ninhydrin and 1,2,3,4-tetrahydroisoquinoline, with the conjugated double bond of chalcone derivatives. The regiochemistry and structures of the cycloadduc
Calix [4]bis(spirodienones) can perform as either 4p or 2p components in cycloaddition reactions with various carbo-and heterodienophiles and with 1,2-benzoquinones leading to the formation of highly functionalized macrocycles. In this Letter we report, highly regio-and stereoselective 1,3-dipolar c
1,3-Dipolar cycloaddition reaction of carbonyl ylide with o-quinones afforded novel highly oxygenated spirocyclic compounds.
N,N'-Diarylbisnitrile imides 2 add regioselectively to ¢t-(benzothiazol-2-yl)cinnamonitriles 3 and ct-(l-methylbenzimidazol-2-yl)cinnamonitriles 7 to yield exclusively the cycloadducts 5,5'-dicyano-4,4',5,5'-tetrahydro[3,3'-bi-lH-pyrazoles] 4 and 8, respectively. Compounds 4 and 8 undergo aromatizat
## Abstract Cycloaddition of an azomethine ylide, generated from ninhydrin and tetrahydroisoquinoline, with chalcones offers a novel diastereoselective synthesis of the target compounds.