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1,3-Dipolar cycloaddition of cyclic α-methoxynitrones, derivatives of 2H-imidazole 1-oxide and 4H-imidazole 3-oxide
✍ Scribed by S. M. Bakunova; I. A. Kirilyuk; I. A. Grigor"ev
- Book ID
- 110300735
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 301 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1573-9171
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📜 SIMILAR VOLUMES
Dihydro-1H-imidazole 3-oxides bearing different substituents at positions 1 and 2 of the heterocycle were shown to react with a wide range of acceptor-substituted alkynes forming corrsponding cycloadductsderivatives of 1,2,3,7a-tetrahydroimidazo[1,2-b]isoxazole. High regioselectivity of this process
The influence of solvents and different structural factors on the rate of 1,3-dipolar cycloaddition reaction of the 4,5-dihydro-1H-imidazole 3-oxide derivatives with alkynes have been studied. Nitrones and alkynes have been ranged by their relative activity in this reaction. Using the DFT calculatio