𝔖 Bobbio Scriptorium
✦   LIBER   ✦

13-cis Retinoic Acid in Combination with Interferon-α Enhances Radiation Sensitivity of Human Squamous Cell Carcinoma Cells of the Oral Cavity

✍ Scribed by Marcel Bläse; Marco-Michael Zaruba; Lan Santo-Hoeltje; Michael Bamberg; Wolfgang Hoffmann; H. Peter Rodemann

Publisher
Springer
Year
1999
Tongue
German
Weight
106 KB
Volume
175
Category
Article
ISSN
0179-7158

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

13-CIS retinoic acid and interferon-α ±
13-CIS retinoic acid and interferon-α ± irradiation in the treatment of squamous-cell carcinomas
✍ Wolfgang Hoffmann; Martina Schiebe; Peter Hirnle; Rainer Souchon; Michael Clemen 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 43 KB 👁 1 views

Pre-clinical data indicate that retinoid/interferon combinations have significant activity in modulating malignant cell growth, differentiation and programmed cell death in different hematologic and solid tumor systems . Clinically, the combination of 13-cis retinoic acid (13cRA) and interferon-a (I

Induction of cell cycle arrest and apopt
Induction of cell cycle arrest and apoptosis by a combined treatment with 13-cis-retinoic acid, interferon-α2a, and α-tocopherol in squamous cell carcinoma of the head and neck
✍ Xin Zhang; Zhuo (Georgia) Chen; Fadlo R. Khuri; Dong M. Shin 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 497 KB

## Abstract ## Background. We have previously conducted phase II trials with a combination of 13‐__cis__‐retinoic acid (13‐cRA), interferon‐α2a (IFN‐α2a), and α‐tocopherol (α‐TF) in patients with advanced oral premalignant lesions and locally advanced head and neck cancer in the adjuvant settings

Combination of alpha-interferon 2a (α-IF
Combination of alpha-interferon 2a (α-IFN 2a) and 13-CIS-retinoic acid (13cRA) in recurrent, pre-treated squamous-cell carcinoma of head and neck (SCCHN)
✍ S. Toma; M. Airoldi; R. Palumbo; P. Raffo; C. Bumma 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 53 KB 👁 1 views

It is well known that survival of patients with advanced squamous-cell carcinoma of the head and neck (SCCHN) has not significantly improved despite recent advances in radiation and chemotherapy treatment. Specifically, a very low objective response rate can be obtained in patients with recurrent SC

Interferon-α-2a with or without 13-cis r
Interferon-α-2a with or without 13-cis retinoic acid in patients with progressive, measurable metastatic renal cell carcinoma : Results of a randomized Phase II study (European Organization for Research and Treatment of Cancer Study 30951)
✍ Sophie D. Fosså; Gerald H. J. Mickisch; Pieter H. M. De Mulder; Simon Horenblas; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB

## Background: In patients with metastatic renal cell carcinoma (mrcc), interferon-alpha (ifn) monotherapy leads to response rates of 5-15%, dependent on the selection of patients. in 1995, preclinical and clinical data indicated an improvement of these results if ifn was combined with 13-cis retin